[114] Activation in the ECS system in MS (and EAE) appears to limit neuronal problems by downregulation of cannabinoid receptors inhibiting GABA synapses like a protecting action to lower neuronal excitotoxic injury. Upregulation of endocannabinoid tone protects neurons from excitotoxicity in parallel that has a therapeutic impact within a mouse https://jaredkudlt.activosblog.com/31966038/rumored-buzz-on-medical-marijuana