The context-dependent nature of SERT regulation is underscored through the loss of colocalization of SERT with focal adhesion proteins in KI synapses. This indicates that the Affiliation of SERT with integrin signaling complexes is not necessary for the regulation of the transporter by constitutive signaling downstream of the “primed” Pro32Pro33 https://garrettbreoz.tinyblogging.com/pro33-an-overview-76109891